InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rab5c

Summary

InnateDB Gene

IDBG-211569.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rab5c

Gene Name

RAB5C, member RAS oncogene family

Synonyms

AI326010; Rabl

Species

Mus musculus

Ensembl Gene

ENSMUSG00000019173

Encoded Proteins

IDBP-211571

RAB5C, member RAS oncogene family

IDBP-266825

RAB5C, member RAS oncogene family

IDBP-537405

RAB5C, member RAS oncogene family

IDBP-539149

RAB5C, member RAS oncogene family

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108774:
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:100715009-100738215

Strand

Reverse strand

Band

Transcripts

ENSMUST00000019317	ENSMUSP00000019317
ENSMUST00000107364	ENSMUSP00000102987
ENSMUST00000155843	ENSMUSP00000123581
ENSMUST00000155500	ENSMUSP00000117656

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019003	GDP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006913	nucleocytoplasmic transport
GO:0007032	endosome organization
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0030100	regulation of endocytosis

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005765	lysosomal membrane
GO:0005811	lipid particle
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0030139	endocytic vesicle
GO:0031901	early endosome membrane
GO:0042470	melanosome
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome