InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nfib

Summary

InnateDB Protein

IDBP-537537.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nfib

Protein Name

nuclear factor I/B

Synonyms

6720429L07Rik; CTF; E030026I10Rik; NF-I/B; NF1-B; NFI-B;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123169

InnateDB Gene

IDBG-159419 (Nfib)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0006260	DNA replication
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0008285	negative regulation of cell proliferation
GO:0030324	lung development
GO:0030900	forebrain development
GO:0030902	hindbrain development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

MGI:103188

InterPro

IPR003619 MAD homology 1, Dwarfin-type
IPR019548 CTF transcription factor/nuclear factor 1, N-terminal
IPR020604 CTF transcription factor/nuclear factor 1, DNA-binding domain

PFAM

PF03165
PF10524

PRINTS

PIRSF

SMART

SM00523

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

J3JS90

UniProt Splice Variant

Entrez Gene

18028

UniGene

Mm.471772

RefSeq

MGI ID

MGI Symbol

Nfib

OMIM

CCDS

HPRD

IMGT

EMBL

AL592283 AL670769 AL773518 BX324149

GenPept

CAM22762