InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Clcn6

Summary

InnateDB Protein

IDBP-537554.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Clcn6

Protein Name

chloride channel 6

Synonyms

AI850629;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121751

InnateDB Gene

IDBG-204011 (Clcn6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005247	voltage-gated chloride channel activity
GO:0030554	adenyl nucleotide binding

Biological Process

GO:0006821	chloride transport
GO:0009612	response to mechanical stimulus
GO:0034220	ion transmembrane transport
GO:0044070	regulation of anion transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005765	lysosomal membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1347049

InterPro

IPR000644 CBS domain
IPR001807 Chloride channel, voltage gated
IPR002248 Chloride channel ClC-6
IPR014743 Chloride channel, core

PFAM

PF00571
PF00654

PRINTS

PR00762
PR01117

PIRSF

SMART

SM00116

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8CJB1

UniProt Splice Variant

Entrez Gene

26372

UniGene

Mm.89987

RefSeq

XP_006536015

MGI ID

MGI Symbol

Clcn6

OMIM

CCDS

HPRD

IMGT

EMBL

AF398931 AL606929 AY046557

GenPept

AAL17643 AAN40866