Version 5.4
Mus musculus Protein: Nphs1
Summary
InnateDB Protein IDBP-537579.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nphs1
Protein Name nephrosis 1 homolog, nephrin (human)
Synonyms nephrin; NephrinB;
Species Mus musculus
Ensembl Protein ENSMUSP00000116500
InnateDB Gene IDBG-169263 (Nphs1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000165 MAPK cascade
GO:0007155 cell adhesion
GO:0007254 JNK cascade
GO:0030838 positive regulation of actin filament polymerization
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1859637
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
PFAM PF07679
PF07686
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9QPI7
UniProt Splice Variant
Entrez Gene 54631
UniGene Mm.437830
RefSeq
MGI ID
MGI Symbol Nphs1
OMIM
CCDS
HPRD
IMGT
EMBL AC149067 AC167970
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca