InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Taf10

Summary

InnateDB Protein

IDBP-537697.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Taf10

Protein Name

TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Synonyms

30kDa; AU041226; Taf2h; TAFII30;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118105

InnateDB Gene

IDBG-204983 (Taf10)

Protein Structure

UniProt Annotation

Function

TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May regulate cyclin E expression. {ECO:0000269PubMed:10469660}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 71 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	71 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0001889	liver development
GO:0006352	DNA-templated transcription, initiation
GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0010468	regulation of gene expression
GO:0035264	multicellular organism growth
GO:0043623	cellular protein complex assembly
GO:0051101	regulation of DNA binding
GO:0070365	hepatocyte differentiation