Version 5.4
Mus musculus Protein: Setd2
Summary
InnateDB Protein IDBP-537752.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Setd2
Protein Name SET domain containing 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000116313
InnateDB Gene IDBG-202203 (Setd2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0018024 histone-lysine N-methyltransferase activity
Biological Process
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001763 morphogenesis of a branching structure
GO:0001843 neural tube closure
GO:0006298 mismatch repair
GO:0006355 regulation of transcription, DNA-templated
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0010452 histone H3-K36 methylation
GO:0010468 regulation of gene expression
GO:0010793 regulation of mRNA export from nucleus
GO:0018023 peptidyl-lysine trimethylation
GO:0030900 forebrain development
GO:0034728 nucleosome organization
GO:0034968 histone lysine methylation
GO:0035441 cell migration involved in vasculogenesis
GO:0048332 mesoderm morphogenesis
GO:0048568 embryonic organ development
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048864 stem cell development
GO:0060039 pericardium development
GO:0060669 embryonic placenta morphogenesis
GO:0060977 coronary vasculature morphogenesis
GO:0097198 histone H3-K36 trimethylation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
Protein Structure and Domains
PDB ID MGI:1918177
InterPro IPR001202 WW domain
IPR001214 SET domain
IPR003616 Post-SET domain
IPR006560 AWS
IPR009078 Ferritin-like superfamily
IPR013257 SRI, Set2 Rpb1 interacting
PFAM PF00397
PF00856
PF08236
PRINTS
PIRSF
SMART SM00456
SM00317
SM00508
SM00570
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt E9Q5F9
PhosphoSite PhosphoSite-NP_001074809
TrEMBL
UniProt Splice Variant
Entrez Gene 235626
UniGene Mm.404631
RefSeq NP_001074809
MGI ID
MGI Symbol Setd2
OMIM
CCDS CCDS40781
HPRD
IMGT
EMBL AC132103 AK173246 BC031601 BC059049
GenPept AAH31601 AAH59049 BAD32524

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca