InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pkp2

Summary

InnateDB Protein

IDBP-537754.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pkp2

Protein Name

plakophilin 2

Synonyms

1200008D14Rik; 1200012P04Rik; AA516617; Pkp2l;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000124898

InnateDB Gene

IDBG-136561 (Pkp2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005080	protein kinase C binding
GO:0005515	protein binding
GO:0019215	intermediate filament binding
GO:0032947	protein complex scaffold

Biological Process

GO:0002159	desmosome assembly
GO:0007507	heart development
GO:0016337	single organismal cell-cell adhesion
GO:0045110	intermediate filament bundle assembly
GO:0048496	maintenance of organ identity
GO:0055010	ventricular cardiac muscle tissue morphogenesis
GO:0086005	ventricular cardiac muscle cell action potential
GO:0086019	cell-cell signaling involved in cardiac conduction
GO:0086069	bundle of His cell to Purkinje myocyte communication
GO:0086091	regulation of heart rate by cardiac conduction

Cellular Component

GO:0005911	cell-cell junction
GO:0005912	adherens junction
GO:0014704	intercalated disc
GO:0030057	desmosome

Protein Structure and Domains

PDB ID

MGI:1914701

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CX59

UniProt Splice Variant

Entrez Gene

67451

UniGene

Mm.2252

RefSeq

MGI ID

MGI Symbol

Pkp2

OMIM

CCDS

HPRD

IMGT

EMBL

AC112943

GenPept