InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Wnt2

Summary

InnateDB Protein

IDBP-537898.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Wnt2

Protein Name

wingless-related MMTV integration site 2

Synonyms

2610510E18Rik; Int1l1; Irp; Mirp; Wnt-2; Wnt2a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120589

InnateDB Gene

IDBG-129144 (Wnt2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005109	frizzled binding

Biological Process

GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0007275	multicellular organismal development
GO:0016055	Wnt signaling pathway
GO:0030182	neuron differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0055009	atrial cardiac muscle tissue morphogenesis
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0060070	canonical Wnt signaling pathway
GO:0060317	cardiac epithelial to mesenchymal transition
GO:0060492	lung induction
GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060716	labyrinthine layer blood vessel development

Cellular Component

GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:98954

InterPro

IPR005817 Wnt
IPR009140 Wnt-2 protein

PFAM

PF00110

PRINTS

PR01349
PR01842

PIRSF

SMART

SM00097

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D6RIJ9

UniProt Splice Variant

Entrez Gene

22413

UniGene

Mm.33653

RefSeq

MGI ID

MGI Symbol

Wnt2

OMIM

CCDS

HPRD

IMGT

EMBL

AC068561

GenPept