InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Erp29

Summary

InnateDB Protein

IDBP-537997.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Erp29

Protein Name

endoplasmic reticulum protein 29

Synonyms

1200015M03Rik; 2810446M09Rik; AW209030; Erp28; Erp31; PDI-Db;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117347

InnateDB Gene

IDBG-197333 (Erp29)

Protein Structure

UniProt Annotation

Function

Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.

Subcellular Localization

Endoplasmic reticulum lumen {ECO:0000255PROSITE-ProRule:PRU10138}. Melanosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0009306

protein secretion

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen
GO:0009986	cell surface
GO:0016020	membrane
GO:0042470	melanosome
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1914647

InterPro

IPR011679 Endoplasmic reticulum, protein ERp29, C-terminal
IPR012336 Thioredoxin-like fold
IPR012883 ERp29, N-terminal
IPR016855 Endoplasmic reticulum, protein ERp29

PFAM

PF07749
PF13098
PF13192
PF13462
PF13905
PF07912

PRINTS

PIRSF

PIRSF027352

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P57759