InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Oprm1

Summary

InnateDB Protein

IDBP-538357.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Oprm1

Protein Name

opioid receptor, mu 1

Synonyms

M-OR-1; MOP-R; mor; MOR-1; MOR-1O; muOR; Oprm;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000122385

InnateDB Gene

IDBG-130147 (Oprm1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004979	beta-endorphin receptor activity
GO:0004985	opioid receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway
GO:0007626	locomotory behavior
GO:0038003	opioid receptor signaling pathway

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:97441

InterPro

IPR000105 Mu opioid receptor
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000586 Somatostatin receptor family
IPR000611 Neuropeptide Y receptor family
IPR001418 Opioid receptor
IPR009150 Neuropeptide B/W receptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019430 7TM GPCR, serpentine receptor class x (Srx)

PFAM

PF00001
PF10320
PF10328

PRINTS

PR00537
PR00237
PR00246
PR01012
PR00384
PR01855

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q99M68

UniProt Splice Variant

Entrez Gene

18390

UniGene

RefSeq

MGI ID

MGI Symbol

Oprm1

OMIM

CCDS

HPRD

IMGT

EMBL

AC153981 AC155718 AC164171 AF347691 AJ308511 AY028944

GenPept

AAK31600 AAL24465 CAC83776