InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pias4

Summary

InnateDB Protein

IDBP-538437.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pias4

Protein Name

protein inhibitor of activated STAT 4

Synonyms

Pias-gamma; Piasg; PIASY;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121361

InnateDB Gene

IDBG-177127 (Pias4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 78 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	78 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0019789	SUMO ligase activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0007259	JAK-STAT cascade
GO:0016925	protein sumoylation
GO:0045087	innate immune response (InnateDB)
GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Cellular Component

GO:0016363

nuclear matrix

Protein Structure and Domains

PDB ID

MGI:2136940

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F6RKH8

UniProt Splice Variant

Entrez Gene

59004

UniGene

Mm.34428

RefSeq

MGI ID

MGI Symbol

Pias4

OMIM

CCDS

HPRD

IMGT

EMBL

AC155932

GenPept