Version 5.4
Mus musculus Protein: Scn5a
Summary
InnateDB Protein IDBP-538909.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scn5a
Protein Name sodium channel, voltage-gated, type V, alpha
Synonyms mH1; Nav1.5; Nav1.5c; SkM1; SkM2;
Species Mus musculus
Ensembl Protein ENSMUSP00000118250
InnateDB Gene IDBG-204746 (Scn5a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005248 voltage-gated sodium channel activity
GO:0005515 protein binding
GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086063 voltage-gated sodium channel activity involved in regulation of SA node cell action potential
Biological Process
GO:0003231 cardiac ventricle development
GO:0006814 sodium ion transport
GO:0014070 response to organic cyclic compound
GO:0019228 neuronal action potential
GO:0035725 sodium ion transmembrane transport
GO:0086004 regulation of cardiac muscle cell contraction
GO:0086012 membrane depolarization during cardiac muscle cell action potential
GO:0086046 membrane depolarization involved in regulation of SA node cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
Cellular Component
GO:0001518 voltage-gated sodium channel complex
GO:0005886 plasma membrane
GO:0014704 intercalated disc
GO:0030315 T-tubule
GO:0034706 sodium channel complex
Protein Structure and Domains
PDB ID MGI:98251
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YXW2
UniProt Splice Variant
Entrez Gene 20271
UniGene Mm.490207
RefSeq
MGI ID
MGI Symbol Scn5a
OMIM
CCDS
HPRD
IMGT
EMBL AC121922 AC171201
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca