Version 5.4
Mus musculus Protein: Stk3
Summary
InnateDB Protein IDBP-538921.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stk3
Protein Name serine/threonine kinase 3 (Ste20, yeast homolog)
Synonyms 0610042I06Rik; mess1; MST; Mst2; Mst3; Ste20;
Species Mus musculus
Ensembl Protein ENSMUSP00000116310
InnateDB Gene IDBG-134139 (Stk3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004702 receptor signaling protein serine/threonine kinase activity
Biological Process
GO:0001841 neural tube formation
GO:0003157 endocardium development
GO:0007417 central nervous system development
GO:0008285 negative regulation of cell proliferation
GO:0023014 signal transduction by phosphorylation
GO:0043065 positive regulation of apoptotic process
GO:0046330 positive regulation of JNK cascade
GO:0046621 negative regulation of organ growth
GO:0051897 positive regulation of protein kinase B signaling
GO:0060215 primitive hemopoiesis
GO:0060706 cell differentiation involved in embryonic placenta development
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0097284 hepatocyte apoptotic process
GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1928487
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RHQ9
UniProt Splice Variant
Entrez Gene 56274
UniGene Mm.460842
RefSeq
MGI ID
MGI Symbol Stk3
OMIM
CCDS
HPRD
IMGT
EMBL AC116950 AC122907
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca