InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Limk1

Summary

InnateDB Protein

IDBP-538955.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Limk1

Protein Name

LIM-domain containing, protein kinase

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118268

InnateDB Gene

IDBG-203064 (Limk1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006468	protein phosphorylation
GO:0045773	positive regulation of axon extension
GO:0051496	positive regulation of stress fiber assembly

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005925	focal adhesion

Protein Structure and Domains

PDB ID

MGI:104572

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR011009 Protein kinase-like domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F6XM68

UniProt Splice Variant

Entrez Gene

16885

UniGene

Mm.15409

RefSeq

MGI ID

MGI Symbol

Limk1

OMIM

CCDS

HPRD

IMGT

EMBL

AC166938

GenPept