InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cd40

Summary

InnateDB Protein

IDBP-539009.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cd40

Protein Name

CD40 antigen

Synonyms

AI326936; Bp50; GP39; HIGM1; IGM; IMD3; p50; T-BAM; Tnfrsf5; TRAP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000122981

InnateDB Gene

IDBG-212533 (Cd40)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.

Experimentally validated
Total	48 [view]
Protein-Protein	43 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	55 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0002768	immune response-regulating cell surface receptor signaling pathway
GO:0030890	positive regulation of B cell proliferation
GO:0032735	positive regulation of interleukin-12 production
GO:0042113	B cell activation
GO:0048304	positive regulation of isotype switching to IgG isotypes
GO:0050776	regulation of immune response
GO:0051023	regulation of immunoglobulin secretion
GO:0051607	defense response to virus

Cellular Component

GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

MGI:88336

InterPro

IPR001368 TNFR/NGFR cysteine-rich region

PFAM

PF00020

PRINTS

PIRSF

SMART

SM00208

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2A5L7

UniProt Splice Variant

Entrez Gene

21939

UniGene

RefSeq

MGI ID

MGI Symbol

Cd40

OMIM

CCDS

HPRD

IMGT

EMBL

AL591411 AL591495

GenPept