InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lcp1

Summary

InnateDB Protein

IDBP-539291.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lcp1

Protein Name

lymphocyte cytosolic protein 1

Synonyms

AW536232; D14Ertd310e; LCP-1; Pls2; pp65;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121376

InnateDB Gene

IDBG-180662 (Lcp1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0042802	identical protein binding
GO:0051015	actin filament binding

Biological Process

GO:0002286	T cell activation involved in immune response
GO:0007165	signal transduction
GO:0031100	organ regeneration
GO:0033157	regulation of intracellular protein transport
GO:0051017	actin filament bundle assembly

Cellular Component

GO:0001726	ruffle
GO:0001891	phagocytic cup
GO:0005578	proteinaceous extracellular matrix
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005884	actin filament

Protein Structure and Domains

PDB ID

MGI:104808

InterPro

IPR002048 EF-hand domain
IPR019577 SPARC/Testican, calcium-binding domain

PFAM

PF00036
PF13202
PF13405
PF10591

PRINTS

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z7D9

UniProt Splice Variant

Entrez Gene

18826

UniGene

Mm.490125

RefSeq

MGI ID

MGI Symbol

Lcp1

OMIM

CCDS

HPRD

IMGT

EMBL

AC129591 AC161877

GenPept