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InnateDB Protein
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IDBP-539332.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Nr6a1
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Protein Name
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nuclear receptor subfamily 6, group A, member 1
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Synonyms
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1700113M01Rik; Gcnf; NCNF; RTR;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000115164
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InnateDB Gene
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IDBG-166859 (Nr6a1)
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Protein Structure
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| Function |
Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis. {ECO:0000269PubMed:7854358}.
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| Subcellular Localization |
Nucleus {ECO:0000305}.
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| Disease Associations |
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| Tissue Specificity |
Expressed in the germ cells of both the adult testis and ovary, being most abundant in spermatids. {ECO:0000269PubMed:7835709, ECO:0000269PubMed:7854358}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
8
[view]
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| Protein-Protein |
7
[view]
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| Protein-DNA |
1
[view]
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
2 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0008270
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zinc ion binding
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GO:0043565
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sequence-specific DNA binding
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| Biological Process |
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GO:0006355
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regulation of transcription, DNA-templated
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| Cellular Component |
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| PDB ID |
MGI:1352459
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| InterPro |
IPR001628
Zinc finger, nuclear hormone receptor-type
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| PFAM |
PF00105
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| PRINTS |
PR00047
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| PIRSF |
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| SMART |
SM00399
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
14536
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| UniGene |
Mm.439703
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Nr6a1
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
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| GenPept |
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Version 5.4