InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ptpn3

Summary

InnateDB Protein

IDBP-539550.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ptpn3

Protein Name

protein tyrosine phosphatase, non-receptor type 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000122490

InnateDB Gene

IDBG-149658 (Ptpn3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001784	phosphotyrosine binding
GO:0008092	cytoskeletal protein binding
GO:0051117	ATPase binding

Biological Process

GO:0006470	protein dephosphorylation
GO:0045930	negative regulation of mitotic cell cycle
GO:0051045	negative regulation of membrane protein ectodomain proteolysis

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0009898	cytoplasmic side of plasma membrane
GO:0019898	extrinsic component of membrane

Protein Structure and Domains

PDB ID

MGI:105307

InterPro

IPR000299 FERM domain
IPR000798 Ezrin/radixin/moesin like
IPR018979 FERM, N-terminal
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR029071 Ubiquitin-related domain

PFAM

PF09379
PF00373

PRINTS

PR00661
PR00935

PIRSF

SMART

SM00295

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2ALL1

UniProt Splice Variant

Entrez Gene

545622

UniGene

Mm.246552

RefSeq

MGI ID

MGI Symbol

Ptpn3

OMIM

CCDS

HPRD

IMGT

EMBL

AL805921

GenPept