Version 5.4
Mus musculus Protein: Gnat2
Summary
InnateDB Protein IDBP-539558.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gnat2
Protein Name guanine nucleotide binding protein, alpha transducing 2
Synonyms AW490837; Gnat-2; Gt-2; Tcalpha;
Species Mus musculus
Ensembl Protein ENSMUSP00000123125
InnateDB Gene IDBG-186203 (Gnat2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001664 G-protein coupled receptor binding
GO:0003924 GTPase activity
GO:0004871 signal transducer activity
GO:0005525 GTP binding
GO:0019001 guanyl nucleotide binding
GO:0031683 G-protein beta/gamma-subunit complex binding
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007601 visual perception
GO:0007602 phototransduction
GO:0009642 response to light intensity
GO:0016056 rhodopsin mediated signaling pathway
GO:0046549 retinal cone cell development
GO:0050908 detection of light stimulus involved in visual perception
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005834 heterotrimeric G-protein complex
GO:0016020 membrane
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
Protein Structure and Domains
PDB ID MGI:95779
InterPro IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR011025 G protein alpha subunit, helical insertion
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00503
PF00025
PRINTS PR00318
PR00328
PIRSF
SMART SM00275
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2AE31
UniProt Splice Variant
Entrez Gene 14686
UniGene Mm.439652
RefSeq
MGI ID
MGI Symbol Gnat2
OMIM
CCDS
HPRD
IMGT
EMBL AL671854
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca