Version 5.4
Mus musculus Protein: Tbp
Summary
InnateDB Protein IDBP-539562.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tbp
Protein Name TATA box binding protein
Synonyms Gtf2d; GTF2D1; SCA17; TFIID;
Species Mus musculus
Ensembl Protein ENSMUSP00000120484
InnateDB Gene IDBG-139921 (Tbp)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 54 experimentally validated interaction(s) in this database.
They are also associated with 146 interaction(s) predicted by orthology.
Experimentally validated
Total 54 [view]
Protein-Protein 46 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 146 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001103 RNA polymerase II repressing transcription factor binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0006352 DNA-templated transcription, initiation
GO:0006366 transcription from RNA polymerase II promoter
GO:0006383 transcription from RNA polymerase III promoter
GO:0007283 spermatogenesis
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0000120 RNA polymerase I transcription factor complex
GO:0001939 female pronucleus
GO:0001940 male pronucleus
GO:0005634 nucleus
GO:0005669 transcription factor TFIID complex
GO:0005672 transcription factor TFIIA complex
GO:0005719 nuclear euchromatin
GO:0005737 cytoplasm
GO:0045120 pronucleus
Protein Structure and Domains
PDB ID MGI:101838
InterPro IPR000814 TATA-box binding protein
PFAM PF00352
PRINTS PR00686
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6LEM2
UniProt Splice Variant
Entrez Gene 21374
UniGene Mm.489273
RefSeq
MGI ID
MGI Symbol Tbp
OMIM
CCDS
HPRD
IMGT
EMBL AC154378 D86619 FJ770049
GenPept ACN86312 BAA21084

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca