InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Spdef

Summary

InnateDB Protein

IDBP-539643.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Spdef

Protein Name

SAM pointed domain containing ets transcription factor

Synonyms

PDEF; Pse;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117743

InnateDB Gene

IDBG-157107 (Spdef)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0010454	negative regulation of cell fate commitment
GO:0010455	positive regulation of cell fate commitment
GO:0043065	positive regulation of apoptotic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060480	lung goblet cell differentiation
GO:0060576	intestinal epithelial cell development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1353422

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B2KF87

UniProt Splice Variant

Entrez Gene

30051

UniGene

RefSeq

MGI ID

MGI Symbol

Spdef

OMIM

CCDS

HPRD

IMGT

EMBL

AC131800

GenPept