InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pus1

Summary

InnateDB Protein

IDBP-539646.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pus1

Protein Name

pseudouridine synthase 1

Synonyms

A730013B20Rik; MPUS1; mPus1p;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115468

InnateDB Gene

IDBG-190350 (Pus1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0009982	pseudouridine synthase activity
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity

Biological Process

GO:0001522	pseudouridine synthesis
GO:0009451	RNA modification
GO:0031119	tRNA pseudouridine synthesis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

MGI:1929237

InterPro

IPR020103 Pseudouridine synthase, catalytic domain

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z092

UniProt Splice Variant

Entrez Gene

56361

UniGene

Mm.23528

RefSeq

MGI ID

MGI Symbol

Pus1

OMIM

CCDS

HPRD

IMGT

EMBL

AC161348

GenPept