InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fbp1

Summary

InnateDB Protein

IDBP-539760.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fbp1

Protein Name

fructose bisphosphatase 1

Synonyms

Fbp-2; Fbp2; Fbp3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115703

InnateDB Gene

IDBG-160648 (Fbp1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016208	AMP binding
GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity
GO:0042578	phosphoric ester hydrolase activity
GO:0042802	identical protein binding
GO:0046872	metal ion binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006002	fructose 6-phosphate metabolic process
GO:0006111	regulation of gluconeogenesis
GO:0016311	dephosphorylation
GO:0030308	negative regulation of cell growth
GO:0035690	cellular response to drug
GO:0045820	negative regulation of glycolytic process
GO:0046580	negative regulation of Ras protein signal transduction
GO:0051289	protein homotetramerization
GO:0071286	cellular response to magnesium ion

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:95492

InterPro

IPR000146 Fructose-1,6-bisphosphatase class 1/Sedoheputulose-1,7-bisphosphatase

PFAM

PF00316

PRINTS

PIRSF

PIRSF000904

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q9QXB3

UniProt Splice Variant

Entrez Gene

14121

UniGene

Mm.423078

RefSeq

MGI ID

MGI Symbol

Fbp1

OMIM

CCDS

HPRD

IMGT

EMBL

AC156572 AC171004 AJ245385

GenPept

CAB65264