InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fbxo6

Summary

InnateDB Protein

IDBP-539789.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fbxo6

Protein Name

F-box protein 6

Synonyms

AA408845; FBG2; Fbs2; Fbx6b; Fbxo6b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123132

InnateDB Gene

IDBG-204245 (Fbxo6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 135 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	135 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0030246	carbohydrate binding

Biological Process

GO:0006516	glycoprotein catabolic process
GO:0016567	protein ubiquitination
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0019005	SCF ubiquitin ligase complex

Protein Structure and Domains

PDB ID

MGI:1354743

InterPro

IPR001810 F-box domain
IPR007397 F-box associated (FBA) domain
IPR008979 Galactose-binding domain-like

PFAM

PF00646
PF12937
PF13013
PF04300

PRINTS

PIRSF

SMART

SM00256

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2A7H3

UniProt Splice Variant

Entrez Gene

50762

UniGene

Mm.27445

RefSeq

MGI ID

MGI Symbol

Fbxo6

OMIM

CCDS

HPRD

IMGT

EMBL

AL606929

GenPept