InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mknk1

Summary

InnateDB Protein

IDBP-539985.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mknk1

Protein Name

MAP kinase-interacting serine/threonine kinase 1

Synonyms

2410048M24Rik; Mnk1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117261

InnateDB Gene

IDBG-176847 (Mknk1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	16 [view]
Protein-Protein	15 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0035556	intracellular signal transduction
GO:0045087	innate immune response (InnateDB)
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand

Cellular Component

Protein Structure and Domains

PDB ID

MGI:894316

InterPro

IPR000719 Protein kinase domain
IPR011009 Protein kinase-like domain

PFAM

PF00069

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F7B478

UniProt Splice Variant

Entrez Gene

17346

UniGene

Mm.209327

RefSeq

MGI ID

MGI Symbol

Mknk1

OMIM

CCDS

HPRD

IMGT

EMBL

AL627085

GenPept