Version 5.4
Mus musculus Protein: Mad2l2
Summary
InnateDB Protein IDBP-540210.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mad2l2
Protein Name MAD2 mitotic arrest deficient-like 2 (yeast)
Synonyms 2310033C13Rik; G1-453-4; MAD2B; repro22; REV7;
Species Mus musculus
Ensembl Protein ENSMUSP00000122774
InnateDB Gene IDBG-204215 (Mad2l2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001102 RNA polymerase II activating transcription factor binding
GO:0008432 JUN kinase binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001558 regulation of cell growth
GO:0006302 double-strand break repair
GO:0007015 actin filament organization
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0042772 DNA damage response, signal transduction resulting in transcription
GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin
GO:2000678 negative regulation of transcription regulatory region DNA binding
Cellular Component
GO:0005680 anaphase-promoting complex
GO:0005819 spindle
GO:0016035 zeta DNA polymerase complex
Protein Structure and Domains
PDB ID MGI:1919140
InterPro IPR003511 DNA-binding HORMA
PFAM PF02301
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2A7G6
UniProt Splice Variant
Entrez Gene 71890
UniGene Mm.9648
RefSeq
MGI ID
MGI Symbol Mad2l2
OMIM
CCDS
HPRD
IMGT
EMBL AL606929
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca