Version 5.4
Mus musculus Protein: Tnfaip8
Summary
InnateDB Protein IDBP-540305.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnfaip8
Protein Name tumor necrosis factor, alpha-induced protein 8
Synonyms AA987150; E130304C20Rik; ENSMUSG00000073567; Gg2-1; Gm10539; Nded; Ssc-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000120712
InnateDB Gene IDBG-146216 (Tnfaip8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Biological Process
GO:0032611 interleukin-1 beta production
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2147191
InterPro IPR008477 Protein of unknown function DUF758
PFAM PF05527
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3QNA5
UniProt Splice Variant
Entrez Gene 106869
UniGene Mm.409549
RefSeq NP_001171230
MGI ID
MGI Symbol Tnfaip8
OMIM
CCDS CCDS50288
HPRD
IMGT
EMBL AC120859 AC166570
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca