Version 5.4
Mus musculus Gene: Tnfaip8
Summary
InnateDB Gene IDBG-146216.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tnfaip8
Gene Name tumor necrosis factor, alpha-induced protein 8
Synonyms AA987150; E130304C20Rik; ENSMUSG00000073567; Gg2-1; Gm10539; Nded; Ssc-2
Species Mus musculus
Ensembl Gene ENSMUSG00000062210
Encoded Proteins
IDBP-540305
tumor necrosis factor, alpha-induced protein 8
IDBP-536929
tumor necrosis factor, alpha-induced protein 8
IDBP-702587
IDBP-702686
IDBP-531771
tumor necrosis factor, alpha-induced protein 8
IDBP-539976
tumor necrosis factor, alpha-induced protein 8
IDBP-539977
tumor necrosis factor, alpha-induced protein 8
IDBP-702648
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145779:
Gene Information
Type Protein coding
Genomic Location Chromosome 18:49979427-50107173
Strand Forward strand
Band D1
Transcripts
ENSMUST00000087655
ENSMUST00000148989 ENSMUSP00000120712
ENSMUST00000153545
ENSMUST00000126666 ENSMUSP00000121372
ENSMUST00000145726 ENSMUSP00000136665
ENSMUST00000124175
ENSMUST00000128377 ENSMUSP00000136152
ENSMUST00000155403
ENSMUST00000134348 ENSMUSP00000119533
ENSMUST00000153873 ENSMUSP00000115396
ENSMUST00000148159 ENSMUSP00000119041
ENSMUST00000179937 ENSMUSP00000136030
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Biological Process
GO:0032611 interleukin-1 beta production
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000145779
View Gene Order
ENSBTAG00000014551
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27740 Mm.409549
RefSeq NM_001177759 NM_001177760 NM_134131 XM_006525480
OMIM
CCDS CCDS37817 CCDS50287 CCDS50288
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca