InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Insig2

Summary

InnateDB Protein

IDBP-540627.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Insig2

Protein Name

insulin induced gene 2

Synonyms

2900053I11Rik; C730043J18Rik; Insig-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123993

InnateDB Gene

IDBG-188177 (Insig2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008134	transcription factor binding

Biological Process

GO:0006641	triglyceride metabolic process
GO:0006695	cholesterol biosynthetic process
GO:0006991	response to sterol depletion
GO:0008203	cholesterol metabolic process
GO:0010894	negative regulation of steroid biosynthetic process
GO:0016126	sterol biosynthetic process
GO:0032868	response to insulin
GO:0032933	SREBP signaling pathway
GO:0042472	inner ear morphogenesis
GO:0042474	middle ear morphogenesis
GO:0045717	negative regulation of fatty acid biosynthetic process
GO:0060021	palate development
GO:0060363	cranial suture morphogenesis
GO:0070542	response to fatty acid

Cellular Component

GO:0032937

SREBP-SCAP-Insig complex

Protein Structure and Domains

PDB ID

MGI:1920249

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CYQ1

UniProt Splice Variant

Entrez Gene

72999

UniGene

Mm.486216

RefSeq

MGI ID

MGI Symbol

Insig2

OMIM

CCDS

HPRD

IMGT

EMBL

AC163333

GenPept