InnateDB Protein
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IDBP-540673.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Sirt6
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Protein Name
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sirtuin 6 (silent mating type information regulation 2, homolog) 6 (S. cerevisiae)
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Synonyms
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2810449N18Rik; AI043036; Sir2l6;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000118238
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InnateDB Gene
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IDBG-179184 (Sirt6)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
2
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
21 [view]
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Molecular Function |
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Biological Process |
GO:0010569
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regulation of double-strand break repair via homologous recombination
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GO:0070932
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histone H3 deacetylation
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Cellular Component |
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PDB ID |
MGI:1354161
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InterPro |
IPR003000
Sirtuin family
IPR026590
Sirtuin family, catalytic core domain
IPR029035
DHS-like NAD/FAD-binding domain
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PFAM |
PF02146
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-
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TrEMBL |
D3YY89
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UniProt Splice Variant |
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Entrez Gene |
50721
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UniGene |
Mm.25643
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RefSeq |
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MGI ID |
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MGI Symbol |
Sirt6
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AC153919
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GenPept |
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