InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ccbe1

Summary

InnateDB Protein

IDBP-540686.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccbe1

Protein Name

collagen and calcium binding EGF domains 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117636

InnateDB Gene

IDBG-154939 (Ccbe1)

Protein Structure

UniProt Annotation

Function

Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005518	collagen binding

Biological Process

GO:0001946	lymphangiogenesis
GO:0002040	sprouting angiogenesis
GO:0010575	positive regulation vascular endothelial growth factor production
GO:0010595	positive regulation of endothelial cell migration
GO:0010954	positive regulation of protein processing
GO:0045766	positive regulation of angiogenesis
GO:0048845	venous blood vessel morphogenesis
GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway
GO:1901492	positive regulation of lymphangiogenesis