Version 5.4
Mus musculus Protein: Rtl1
Summary
InnateDB Protein IDBP-540862.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rtl1
Protein Name retrotransposon-like 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000115957
InnateDB Gene IDBG-488855 (Rtl1)
Protein Structure
UniProt Annotation
Function Plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta. {ECO:0000269PubMed:18176565}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in placenta and in various tissues in late-fetal stage. {ECO:0000269PubMed:18176565}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007275 multicellular organismal development
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2656842
InterPro IPR005162 Retrotransposon gag domain
IPR021109 Aspartic peptidase domain
PFAM PF03732
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7M732
PhosphoSite PhosphoSite-
TrEMBL B4YB44
UniProt Splice Variant
Entrez Gene 353326
UniGene Mm.490311
RefSeq NP_908998
MGI ID
MGI Symbol Rtl1
OMIM
CCDS CCDS26170
HPRD
IMGT
EMBL AC152063 BK001261 EU434913 EU434918
GenPept ACF20046 ACF20051 DAA01153

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca