InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Htr2b

Summary

InnateDB Protein

IDBP-540954.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Htr2b

Protein Name

5-hydroxytryptamine (serotonin) receptor 2B

Synonyms

5-HT2B; AJ012488; AV377389;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000116273

InnateDB Gene

IDBG-176588 (Htr2b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004993	serotonin receptor activity
GO:0051378	serotonin binding

Biological Process

GO:0006939	smooth muscle contraction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007208	phospholipase C-activating serotonin receptor signaling pathway
GO:0007507	heart development
GO:0042310	vasoconstriction
GO:0050795	regulation of behavior

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

MGI:109323

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019430 7TM GPCR, serpentine receptor class x (Srx)

PFAM

PF00001
PF10320
PF10328

PRINTS

PR00237

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3UVT8

UniProt Splice Variant

Entrez Gene

15559

UniGene

Mm.439747

RefSeq

MGI ID

MGI Symbol

Htr2b

OMIM

CCDS

HPRD

IMGT

EMBL

AC157768 CH466520

GenPept

EDL40239