InnateDB Protein
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IDBP-540967.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Fancc
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Protein Name
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Fanconi anemia, complementation group C
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Synonyms
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Facc;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000124406
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InnateDB Gene
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IDBG-160833 (Fancc)
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Protein Structure
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Function |
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1 (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=The major form is nuclear. The minor form is cytoplasmic.
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Disease Associations |
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Tissue Specificity |
Ubiquitous.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Experimentally validated |
Total |
7
[view]
|
Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
32 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:95480
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InterPro |
IPR000686
Fanconi anaemia group C protein
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PFAM |
PF02106
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PRINTS |
PR00494
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PIRSF |
PIRSF018417
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P50652
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PhosphoSite |
PhosphoSite-P50652
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TrEMBL |
E0CYY7
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UniProt Splice Variant |
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Entrez Gene |
14088
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UniGene |
Mm.465019
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RefSeq |
XP_006517150
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MGI ID |
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MGI Symbol |
Fancc
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AC130827
AC154638
CT009757
L08266
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GenPept |
AAA37590
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