Version 5.4
Mus musculus Protein: Myo7a
Summary
InnateDB Protein IDBP-541000.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myo7a
Protein Name myosin VIIA
Synonyms Hdb; Myo7; nmf371; polka; sh-1; sh1; USH1B;
Species Mus musculus
Ensembl Protein ENSMUSP00000114944
InnateDB Gene IDBG-200041 (Myo7a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019904 protein domain specific binding
GO:0030507 spectrin binding
Biological Process
GO:0001845 phagolysosome assembly
GO:0006886 intracellular protein transport
GO:0006909 phagocytosis
GO:0007600 sensory perception
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0008152 metabolic process
GO:0030030 cell projection organization
GO:0042472 inner ear morphogenesis
GO:0042490 mechanoreceptor differentiation
GO:0042491 auditory receptor cell differentiation
GO:0048563 post-embryonic organ morphogenesis
GO:0048839 inner ear development
GO:0050953 sensory perception of light stimulus
GO:0051875 pigment granule localization
GO:0051904 pigment granule transport
GO:0060088 auditory receptor cell stereocilium organization
GO:0060113 inner ear receptor cell differentiation
Cellular Component
GO:0005737 cytoplasm
GO:0005902 microvillus
GO:0016324 apical plasma membrane
GO:0016459 myosin complex
GO:0032391 photoreceptor connecting cilium
GO:0032420 stereocilium
GO:0042470 melanosome
Protein Structure and Domains
PDB ID MGI:104510
InterPro IPR001609 Myosin head, motor domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00063
PRINTS PR00193
PIRSF
SMART SM00242
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YUT5
UniProt Splice Variant
Entrez Gene 17921
UniGene Mm.1403
RefSeq
MGI ID
MGI Symbol Myo7a
OMIM
CCDS
HPRD
IMGT
EMBL AC115022 AC157792
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca