Version 5.4
Mus musculus Protein: Cacna1b
Summary
InnateDB Protein IDBP-541082.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cacna1b
Protein Name calcium channel, voltage-dependent, N type, alpha 1B subunit
Synonyms alpha(1B); AW050276; AW060892; AW822256; Cav2.2; Cchn1a;
Species Mus musculus
Ensembl Protein ENSMUSP00000114605
InnateDB Gene IDBG-142643 (Cacna1b)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005245 voltage-gated calcium channel activity
GO:0005515 protein binding
GO:0008331 high voltage-gated calcium channel activity
Biological Process
GO:0006816 calcium ion transport
GO:0007269 neurotransmitter secretion
GO:0007626 locomotory behavior
GO:0008016 regulation of heart contraction
GO:0008217 regulation of blood pressure
GO:0048265 response to pain
GO:0051924 regulation of calcium ion transport
GO:0070509 calcium ion import
GO:0070588 calcium ion transmembrane transport
GO:0086010 membrane depolarization during action potential
Cellular Component
GO:0005891 voltage-gated calcium channel complex
GO:0016020 membrane
GO:0030425 dendrite
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID MGI:88296
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2AJ01
UniProt Splice Variant
Entrez Gene 12287
UniGene Mm.4424
RefSeq
MGI ID
MGI Symbol Cacna1b
OMIM
CCDS
HPRD
IMGT
EMBL AL732525 AL732546 BX294112
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca