Version 5.4
Mus musculus Protein: Egfl7
Summary
InnateDB Protein IDBP-541207.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Egfl7
Protein Name EGF-like domain 7
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000115482
InnateDB Gene IDBG-149717 (Egfl7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005112 Notch binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001525 angiogenesis
GO:0001568 blood vessel development
GO:0001570 vasculogenesis
GO:0001938 positive regulation of endothelial cell proliferation
GO:0007155 cell adhesion
GO:0030334 regulation of cell migration
GO:0030336 negative regulation of cell migration
GO:0045746 negative regulation of Notch signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:2449923
InterPro IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR011489 EMI domain
PFAM PF00008
PF07645
PF07546
PRINTS
PIRSF
SMART SM00181
SM00179
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3UTJ7
UniProt Splice Variant
Entrez Gene 353156
UniGene Mm.268933
RefSeq XP_006498204
MGI ID
MGI Symbol Egfl7
OMIM
CCDS CCDS15807
HPRD
IMGT
EMBL AF184973 AK002601 AK139377 AL732311 AY239289 AY239290 AY309459 BC024610 BX649422
GenPept AAF01322 AAH24610 AAP69825 AAP69826 AAP74732 BAB22222 BAE23983

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca