Version 5.4
Mus musculus Gene: Egfl7
Summary
InnateDB Gene IDBG-149717.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Egfl7
Gene Name EGF-like domain 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000026921
Encoded Proteins
IDBP-149719
EGF-like domain 7
IDBP-149725
EGF-like domain 7
IDBP-537705
EGF-like domain 7
IDBP-534406
EGF-like domain 7
IDBP-541207
EGF-like domain 7
IDBP-537782
EGF-like domain 7
IDBP-538778
EGF-like domain 7
IDBP-627540
EGF-like domain 7
IDBP-627539
EGF-like domain 7
IDBP-627533
EGF-like domain 7
IDBP-627536
EGF-like domain 7
IDBP-627537
EGF-like domain 7
IDBP-627538
EGF-like domain 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172889:
This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:26580014-26593120
Strand Forward strand
Band A3
Transcripts
ENSMUST00000102907 ENSMUSP00000099971
ENSMUST00000100290 ENSMUSP00000097863
ENSMUST00000152713 ENSMUSP00000121896
ENSMUST00000139801 ENSMUSP00000123465
ENSMUST00000150404 ENSMUSP00000115482
ENSMUST00000149460
ENSMUST00000145575 ENSMUSP00000118924
ENSMUST00000147351
ENSMUST00000131112 ENSMUSP00000122245
ENSMUST00000149789 ENSMUSP00000133465
ENSMUST00000152988 ENSMUSP00000133968
ENSMUST00000166920 ENSMUSP00000128741
ENSMUST00000174211 ENSMUSP00000134034
ENSMUST00000173920 ENSMUSP00000134503
ENSMUST00000174572
ENSMUST00000174656 ENSMUSP00000134186
ENSMUST00000173777
ENSMUST00000174465
ENSMUST00000172683
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005112 Notch binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001525 angiogenesis
GO:0001568 blood vessel development
GO:0001570 vasculogenesis
GO:0001938 positive regulation of endothelial cell proliferation
GO:0007155 cell adhesion
GO:0030334 regulation of cell migration
GO:0030336 negative regulation of cell migration
GO:0045746 negative regulation of Notch signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000172889
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.268933
RefSeq NM_001164564 NM_178444 NM_198724 NM_198725 XM_006498142
OMIM
CCDS CCDS15807 CCDS15808
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca