InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mbd2

Summary

InnateDB Protein

IDBP-541258.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mbd2

Protein Name

methyl-CpG binding domain protein 2

Synonyms

MBD2a;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120508

InnateDB Gene

IDBG-157229 (Mbd2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003729	mRNA binding
GO:0008327	methyl-CpG binding
GO:0035197	siRNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0030177	positive regulation of Wnt signaling pathway
GO:0042127	regulation of cell proliferation
GO:0042711	maternal behavior
GO:0043623	cellular protein complex assembly

Cellular Component

GO:0000118	histone deacetylase complex
GO:0000785	chromatin
GO:0000792	heterochromatin
GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1333813

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F6UPR7

UniProt Splice Variant

Entrez Gene

17191

UniGene

Mm.472126

RefSeq

MGI ID

MGI Symbol

Mbd2

OMIM

CCDS

HPRD

IMGT

EMBL

AC134831 AC166815 AC170591

GenPept