InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pdia3

Summary

InnateDB Protein

IDBP-541781.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pdia3

Protein Name

protein disulfide isomerase associated 3

Synonyms

58kDa; Erp; ERp57; ERp60; ERp61; Grp58; PDI; PDI-Q2; PI-PLC; PLC[a]; Plca;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119337

InnateDB Gene

IDBG-202293 (Pdia3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 60 interaction(s) predicted by orthology.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	60 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003756	protein disulfide isomerase activity
GO:0005515	protein binding
GO:0015035	protein disulfide oxidoreductase activity
GO:0016853	isomerase activity

Biological Process

GO:0006457	protein folding
GO:0006662	glycerol ether metabolic process
GO:0034976	response to endoplasmic reticulum stress
GO:0045454	cell redox homeostasis
GO:0055114	oxidation-reduction process
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0009986	cell surface

Protein Structure and Domains

PDB ID

MGI:95834

InterPro

IPR005788 Disulphide isomerase
IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain

PFAM

PF13098
PF13192
PF13462
PF13905
PF00085

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F6Q404

UniProt Splice Variant

Entrez Gene

14827

UniGene

Mm.395115

RefSeq

MGI ID

MGI Symbol

Pdia3

OMIM

CCDS

HPRD

IMGT

EMBL

AL845466

GenPept