InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Grm8

Summary

InnateDB Protein

IDBP-541885.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Grm8

Protein Name

glutamate receptor, metabotropic 8

Synonyms

A230002O04; Gprc1h; mGluR8;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120394

InnateDB Gene

IDBG-130430 (Grm8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001642	group III metabotropic glutamate receptor activity

Biological Process

GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0030818	negative regulation of cAMP biosynthetic process
GO:0051966	regulation of synaptic transmission, glutamatergic

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0042734	presynaptic membrane

Protein Structure and Domains

PDB ID

MGI:1351345

InterPro

IPR000144 GPCR, family 3, metabotropic glutamate receptor 8
IPR000162 GPCR, family 3, metabotropic glutamate receptor
IPR000337 GPCR, family 3
IPR001786 GPCR, family 3, metabotropic glutamate receptor 4
IPR001828 Extracellular ligand-binding receptor
IPR028082 Periplasmic binding protein-like I

PFAM

PF01094

PRINTS

PR01058
PR00593
PR00248
PR01054

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite