InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Celsr2

Summary

InnateDB Protein

IDBP-541982.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Celsr2

Protein Name

cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)

Synonyms

EGFL2; flamingo; Flamingo1; mfmi1; mKIAA0279;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000122516

InnateDB Gene

IDBG-187099 (Celsr2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0001764	neuron migration
GO:0003341	cilium movement
GO:0021591	ventricular system development
GO:0032880	regulation of protein localization
GO:0033326	cerebrospinal fluid secretion
GO:0042384	cilium assembly

Cellular Component

GO:0005886

plasma membrane

Protein Structure and Domains

PDB ID

MGI:1858235

InterPro

IPR000742 Epidermal growth factor-like domain
IPR001791 Laminin G domain
IPR001881 EGF-like calcium-binding domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily

PFAM

PF00008
PF00054
PF02210
PF07645

PRINTS

PIRSF

SMART

SM00181
SM00210
SM00282
SM00179

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite