Version 5.4
Mus musculus Protein: G6pdx
Summary
InnateDB Protein IDBP-542153.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol G6pdx
Protein Name glucose-6-phosphate dehydrogenase X-linked
Synonyms G28A; G6pd; Gpdx;
Species Mus musculus
Ensembl Protein ENSMUSP00000115915
InnateDB Gene IDBG-156374 (G6pdx)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004345 glucose-6-phosphate dehydrogenase activity
GO:0042803 protein homodimerization activity
GO:0050661 NADP binding
Biological Process
GO:0001816 cytokine production
GO:0001998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0002033 vasodilation by angiotensin involved in regulation of systemic arterial blood pressure
GO:0006006 glucose metabolic process
GO:0006098 pentose-phosphate shunt
GO:0006741 NADP biosynthetic process
GO:0006749 glutathione metabolic process
GO:0006979 response to oxidative stress
GO:0019322 pentose biosynthetic process
GO:0032613 interleukin-10 production
GO:0032615 interleukin-12 production
GO:0040014 regulation of multicellular organism growth
GO:0048821 erythrocyte development
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID MGI:105979
InterPro IPR001282 Glucose-6-phosphate dehydrogenase
IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding
IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal
PFAM PF00479
PF02781
PRINTS PR00079
PIRSF PIRSF000110
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A3KG36
UniProt Splice Variant
Entrez Gene 14381
UniGene Mm.27210
RefSeq
MGI ID
MGI Symbol G6pdx
OMIM
CCDS
HPRD
IMGT
EMBL AL669976 AL807376
GenPept CAO77898

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca