InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ppp3cb

Summary

InnateDB Protein

IDBP-542269.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ppp3cb

Protein Name

protein phosphatase 3, catalytic subunit, beta isoform

Synonyms

1110063J16Rik; Calnb; Cnab; CnAbeta;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125630

InnateDB Gene

IDBG-135249 (Ppp3cb)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004722	protein serine/threonine phosphatase activity
GO:0016787	hydrolase activity

Biological Process

GO:0001915	negative regulation of T cell mediated cytotoxicity
GO:0006470	protein dephosphorylation
GO:0007507	heart development
GO:0010468	regulation of gene expression
GO:0030217	T cell differentiation
GO:0031987	locomotion involved in locomotory behavior
GO:0034097	response to cytokine
GO:0043029	T cell homeostasis

Cellular Component

Protein Structure and Domains

PDB ID

MGI:107163

InterPro

IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
IPR029052 Metallo-dependent phosphatase-like

PFAM

PF00149

PRINTS

PR00114

PIRSF

SMART

SM00156

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CZ78

UniProt Splice Variant

Entrez Gene

19056

UniGene

Mm.474197

RefSeq

MGI ID

MGI Symbol

Ppp3cb

OMIM

CCDS

HPRD

IMGT

EMBL

AC146594

GenPept