InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ppp3cb

Summary

InnateDB Gene

IDBG-135249.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ppp3cb

Gene Name

protein phosphatase 3, catalytic subunit, beta isoform

Synonyms

1110063J16Rik; Calnb; Cnab; CnAbeta

Species

Mus musculus

Ensembl Gene

ENSMUSG00000021816

Encoded Proteins

IDBP-135251

protein phosphatase 3, catalytic subunit, beta isoform

IDBP-535799

protein phosphatase 3, catalytic subunit, beta isoform

IDBP-542269

protein phosphatase 3, catalytic subunit, beta isoform

IDBP-533305

protein phosphatase 3, catalytic subunit, beta isoform

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107758:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 14:20499364-20546573

Strand

Reverse strand

Band

Transcripts

ENSMUST00000022355	ENSMUSP00000022355
ENSMUST00000159027	ENSMUSP00000125722
ENSMUST00000161445	ENSMUSP00000125630
ENSMUST00000162217
ENSMUST00000161989	ENSMUSP00000125582
ENSMUST00000162107
ENSMUST00000160812
ENSMUST00000161332

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004722	protein serine/threonine phosphatase activity
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0008144	drug binding
GO:0016787	hydrolase activity
GO:0019899	enzyme binding
GO:0030346	protein phosphatase 2B binding
GO:0033192	calmodulin-dependent protein phosphatase activity
GO:0046983	protein dimerization activity

Biological Process

GO:0001915	negative regulation of T cell mediated cytotoxicity
GO:0006468	protein phosphorylation
GO:0006470	protein dephosphorylation
GO:0007507	heart development
GO:0010468	regulation of gene expression
GO:0017156	calcium ion-dependent exocytosis
GO:0030217	T cell differentiation
GO:0031987	locomotion involved in locomotory behavior
GO:0034097	response to cytokine
GO:0035176	social behavior
GO:0035690	cellular response to drug
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0043029	T cell homeostasis
GO:0050796	regulation of insulin secretion