InnateDB Protein
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IDBP-542282.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gng2
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Protein Name
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guanine nucleotide binding protein (G protein), gamma 2
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Synonyms
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82;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000124725
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InnateDB Gene
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IDBG-134150 (Gng2)
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Protein Structure
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Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Adrenal gland and brain.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
18 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:102705
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InterPro |
IPR001770
G-protein, gamma subunit
IPR015898
G-protein gamma-like domain
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PFAM |
PF00631
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PRINTS |
PR00321
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PIRSF |
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SMART |
SM00224
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TIGRFAMs |
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Modification |
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SwissProt |
P63213
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PhosphoSite |
PhosphoSite-P63213
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
14702
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UniGene |
Mm.452554
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RefSeq |
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MGI ID |
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MGI Symbol |
Gng2
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OMIM |
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CCDS |
CCDS26840
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HPRD |
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IMGT |
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EMBL |
AF098488
AF098489
AK003588
AK012405
AK036138
AK075698
AK158697
AK160396
BC021599
U38496
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GenPept |
AAB01727
AAD16272
AAH21599
BAB22878
BAB28219
BAC29316
BAC35896
BAE34615
BAE35765
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