Version 5.4
| Mus musculus Gene: Gng2 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-134150.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Gng2 | ||||||||||||||||||||||
| Gene Name | guanine nucleotide binding protein (G protein), gamma 2 | ||||||||||||||||||||||
| Synonyms | 82 | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000043004 | ||||||||||||||||||||||
| Encoded Proteins |
guanine nucleotide binding protein (G protein), gamma 2
guanine nucleotide binding protein (G protein), gamma 2
guanine nucleotide binding protein (G protein), gamma 2
guanine nucleotide binding protein (G protein), gamma 2
guanine nucleotide binding protein (G protein), gamma 2
guanine nucleotide binding protein (G protein), gamma 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186469:
This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules. [provided by RefSeq, Aug 2011] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 14:19872559-19977627 | ||||||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||||||
| Band | A3 | ||||||||||||||||||||||
| Transcripts | |||||||||||||||||||||||
| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
G alpha (s) signalling events pathway
Inwardly rectifying K+ channels pathway
Glucagon-type ligand receptors pathway
GPCR downstream signaling pathway
Platelet homeostasis pathway
Hemostasis pathway
Signaling by Wnt pathway
Thromboxane signalling through TP receptor pathway
Signaling by GPCR pathway
Glucagon signaling in metabolic regulation pathway
Class B/2 (Secretin family receptors) pathway
Integration of energy metabolism pathway
G protein gated Potassium channels pathway
G beta:gamma signalling through PLC beta pathway
Activation of Kainate Receptors upon glutamate binding pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
beta-catenin independent WNT signaling pathway
Metabolism pathway
Platelet activation, signaling and aggregation pathway
Activation of GABAB receptors pathway
Aquaporin-mediated transport pathway
Regulation of insulin secretion pathway
Prostacyclin signalling through prostacyclin receptor pathway
G-protein activation pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Potassium Channels pathway
G alpha (12/13) signalling events pathway
ADP signalling through P2Y purinoceptor 12 pathway
GABA B receptor activation pathway
GPCR ligand binding pathway
G alpha (z) signalling events pathway
Ca2+ pathway pathway
Transmembrane transport of small molecules pathway
GABA receptor activation pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
ADP signalling through P2Y purinoceptor 1 pathway
G alpha (i) signalling events pathway
Neuronal System pathway
G alpha (q) signalling events pathway
Opioid Signalling pathway
Presynaptic function of Kainate receptors pathway
G-protein beta:gamma signalling pathway
Signal Transduction pathway
G beta:gamma signalling through PI3Kgamma pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
Transmission across Chemical Synapses pathway
Activation of G protein gated Potassium channels pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Signal amplification pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
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| KEGG |
Chemokine signaling pathway pathway
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| INOH |
GPCR Adenosine A2A receptor signaling pathway pathway
GPCR GroupI metabotropic glutamate receptor signaling pathway pathway
GPCR Dopamine D1like receptor signaling pathway pathway
GPCR signaling pathway
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| PID NCI | |||||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Prostacyclin signalling through prostacyclin receptor pathway
Platelet homeostasis pathway
ADP signalling through P2Y purinoceptor 12 pathway
ADP signalling through P2Y purinoceptor 1 pathway
Thromboxane signalling through TP receptor pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G alpha (i) signalling events pathway
G beta:gamma signalling through PI3Kgamma pathway
G beta:gamma signalling through PLC beta pathway
G alpha (12/13) signalling events pathway
G alpha (s) signalling events pathway
G alpha (z) signalling events pathway
Glucagon-type ligand receptors pathway
Class B/2 (Secretin family receptors) pathway
G-protein activation pathway
Opioid Signalling pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
GABA B receptor activation pathway
Presynaptic function of Kainate receptors pathway
Activation of G protein gated Potassium channels pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Regulation of insulin secretion pathway
Glucagon signaling in metabolic regulation pathway
Integration of energy metabolism pathway
Transmembrane transport of small molecules pathway
Ca2+ pathway pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Neuronal System pathway
Signaling by GPCR pathway
GABA receptor activation pathway
G protein gated Potassium channels pathway
Platelet activation, signaling and aggregation pathway
G-protein beta:gamma signalling pathway
Activation of GABAB receptors pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Inwardly rectifying K+ channels pathway
Activation of Kainate Receptors upon glutamate binding pathway
Potassium Channels pathway
Transmission across Chemical Synapses pathway
GPCR ligand binding pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
Signal amplification pathway
Aquaporin-mediated transport pathway
Hemostasis pathway
Signaling by Wnt pathway
Aquaporin-mediated transport pathway
Activation of Kainate Receptors upon glutamate binding pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GABA B receptor activation pathway
G-protein activation pathway
Regulation of insulin secretion pathway
Glucagon-type ligand receptors pathway
Signaling by GPCR pathway
G alpha (s) signalling events pathway
Prostacyclin signalling through prostacyclin receptor pathway
G protein gated Potassium channels pathway
GABA receptor activation pathway
Activation of GABAB receptors pathway
Hemostasis pathway
Inwardly rectifying K+ channels pathway
Integration of energy metabolism pathway
Transmission across Chemical Synapses pathway
Platelet activation, signaling and aggregation pathway
Transmembrane transport of small molecules pathway
Activation of G protein gated Potassium channels pathway
ADP signalling through P2Y purinoceptor 12 pathway
Ca2+ pathway pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Signal amplification pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
beta-catenin independent WNT signaling pathway
Platelet homeostasis pathway
ADP signalling through P2Y purinoceptor 1 pathway
G alpha (q) signalling events pathway
GPCR downstream signaling pathway
Thromboxane signalling through TP receptor pathway
GPCR ligand binding pathway
Neuronal System pathway
Metabolism pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
G alpha (12/13) signalling events pathway
G-protein beta:gamma signalling pathway
G beta:gamma signalling through PLC beta pathway
Opioid Signalling pathway
Glucagon signaling in metabolic regulation pathway
Presynaptic function of Kainate receptors pathway
Class B/2 (Secretin family receptors) pathway
G beta:gamma signalling through PI3Kgamma pathway
Potassium Channels pathway
G alpha (z) signalling events pathway
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| KEGG |
Chemokine signaling pathway pathway
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| INOH | |||||||||||||||||||||||
| PID NCI |
Nongenotropic Androgen signaling
Rapid glucocorticoid signaling
Thromboxane A2 receptor signaling
IL8- and CXCR2-mediated signaling events
LPA receptor mediated events
CXCR4-mediated signaling events
IL8- and CXCR1-mediated signaling events
PAR1-mediated thrombin signaling events
Signaling events mediated by HDAC Class II
Plasma membrane estrogen receptor signaling
PAR4-mediated thrombin signaling events
Hedgehog signaling events mediated by Gli proteins
CXCR3-mediated signaling events
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| Cross-References | |||||||||||||||||||||||
| SwissProt | P63213 | ||||||||||||||||||||||
| TrEMBL | |||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | 14702 | ||||||||||||||||||||||
| UniGene | Mm.405900 Mm.405928 Mm.415431 Mm.41737 Mm.427578 Mm.452554 | ||||||||||||||||||||||
| RefSeq | NM_001038637 NM_001285908 NM_001285909 NM_001285910 NM_001285911 NM_010315 XM_006518562 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS26840 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | MGI:102705 | ||||||||||||||||||||||
| MGI Symbol | Gng2 | ||||||||||||||||||||||
| EMBL | AF098488 AF098489 AK003588 AK012405 AK036138 AK075698 AK158697 AK160396 BC021599 U38496 | ||||||||||||||||||||||
| GenPept | AAB01727 AAD16272 AAH21599 BAB22878 BAB28219 BAC29316 BAC35896 BAE34615 BAE35765 | ||||||||||||||||||||||
| RNA Seq Atlas | 14702 | ||||||||||||||||||||||