InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Spg7

Summary

InnateDB Protein

IDBP-542294.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Spg7

Protein Name

spastic paraplegia 7 homolog (human)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119552

InnateDB Gene

IDBG-198199 (Spg7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004222	metalloendopeptidase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008270	zinc ion binding
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity

Biological Process

GO:0006508	proteolysis
GO:0007005	mitochondrion organization
GO:0007155	cell adhesion
GO:0008089	anterograde axon cargo transport
GO:0030155	regulation of cell adhesion

Cellular Component

GO:0005739	mitochondrion
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2385906

InterPro

IPR000642 Peptidase M41
IPR003593 AAA+ ATPase domain
IPR003959 ATPase, AAA-type, core
IPR005936 Peptidase, FtsH
IPR011546 Peptidase M41, FtsH extracellular
IPR011704 ATPase, dynein-related, AAA domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF01434
PF00004
PF07724
PF13304
PF06480
PF07728

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite