InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Abi1

Summary

InnateDB Protein

IDBP-542493.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Abi1

Protein Name

abl-interactor 1

Synonyms

E3B1; NAP1; Ssh3bp1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000116093

InnateDB Gene

IDBG-141468 (Abi1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 35 experimentally validated interaction(s) in this database.
They are also associated with 60 interaction(s) predicted by orthology.

Experimentally validated
Total	35 [view]
Protein-Protein	35 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	60 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0030296	protein tyrosine kinase activator activity

Biological Process

GO:0001756	somitogenesis
GO:0009987	cellular process
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0035855	megakaryocyte development
GO:0061098	positive regulation of protein tyrosine kinase activity
GO:0072673	lamellipodium morphogenesis

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0030027	lamellipodium
GO:0031252	cell leading edge

Protein Structure and Domains

PDB ID

MGI:104913

InterPro

IPR000727 Target SNARE coiled-coil domain
IPR001452 SH3 domain
IPR011511 Variant SH3 domain
IPR012849 Abl-interactor, homeo-domain homologous domain

PFAM

PF05739
PF00018
PF14604
PF07653
PF07815

PRINTS

PR00452

PIRSF

SMART

SM00397
SM00326

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B7ZCU5

UniProt Splice Variant

Entrez Gene

11308

UniGene

Mm.487780

RefSeq

MGI ID

MGI Symbol

Abi1

OMIM

CCDS

HPRD

IMGT

EMBL

AL845257 CT030013

GenPept