InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tnfrsf1b

Summary

InnateDB Protein

IDBP-542830.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tnfrsf1b

Protein Name

tumor necrosis factor receptor superfamily, member 1b

Synonyms

CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2; TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr2; TNFR80; TNFRII;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115702

InnateDB Gene

IDBG-203277 (Tnfrsf1b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 106 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	106 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005031	tumor necrosis factor-activated receptor activity
GO:0005515	protein binding

Biological Process

GO:0006954	inflammatory response
GO:0007166	cell surface receptor signaling pathway
GO:0008283	cell proliferation
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
GO:0033209	tumor necrosis factor-mediated signaling pathway
GO:0050728	negative regulation of inflammatory response
GO:0050779	RNA destabilization
GO:0097191	extrinsic apoptotic signaling pathway

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

MGI:1314883

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D6RG55

UniProt Splice Variant

Entrez Gene

21938

UniGene

Mm.466144

RefSeq

MGI ID

MGI Symbol

Tnfrsf1b

OMIM

CCDS

HPRD

IMGT

EMBL

AL627099 AL731675

GenPept